Phenytoin and gingival hyperplasia
WebSep 26, 2024 · anti-seizure drugs, such as phenytoin. immunosuppressants, such as cyclosporine and tacrolimus. calcium channel blockers, such as nifedipine and … WebSep 19, 2024 · Phenytoin, cyclosporin, and nifedipine are the most common causes of gingival overgrowth, and phenytoin has the highest prevalence …
Phenytoin and gingival hyperplasia
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WebOct 30, 2024 · Several distinct classes of drugs, such as anticonvulsants, immunosuppressants, and calcium channel blockers, caused gingival overgrowth. One of the main drugs associated with the gingival overgrowth is the anti-epileptic such as phenytoin, which affects gingival tissues by altering extracellular matrix metabolism. WebNon-inflamed gingival enlargement tends to be a darker red or purple. It may be soft, which bleeds easily, or firm and fibrous. It is also more likely to occur in those with poor dental hygiene. Causes include: Medications, most often ciclosporin, phenytoin and other anticonvulsants, calcium channel blockers.
WebNational Center for Biotechnology Information WebGingival hyperplasia was very common in patients taking PHT (16%-94% of patients). Alveolar bone loss occurred in patients taking carbamazepine or PHT. Patients taking valproate, carbamazepine or phenobarbital also had gingival hyperplasia. We found no published studies of newer-generation AEDs.
WebSep 17, 2024 · Introduction. Drug-induced gingival overgrowth occurs as a side effect of medications such as calcium channel blockers, antiepilepsy drugs, and immunosuppressants, 1 which induce overaccumulation of connective tissue and increase the number of fibroblasts (hyperplasia) in the gingival tissue. 2, 3 Dihydropyridines are a … WebWhich drugs can cause gingival hyperplasia? Drug-induced gingival overgrowth is a side effect associated principally with 3 types of drugs: anticonvulsant (phenytoin), ... The most commonly implicated drugs associated with gingival enlargement are: 1. Phenytoin: an anticonvulsant medication used to treat various types of seizures and convulsions.
WebFeb 13, 2024 · Some medications have been found to cause gingival hyperplasia as a side-effect. Drugs that may be associated with gingival hyperplasia include: Phenytoin (medication to prevent seizures) Cyclosporine (medication to reduce the activity of your immune system) Calcium channel blockers (medications used to manage cardiovascular …
WebMar 26, 2024 · No age predilection exists for the onset of drug-induced gingival overgrowth; however, phenytoin-induced gingival overgrowth appears to be more frequent in young … honda in the newsWebGingival overgrowth (GO), hypertrophic gingivitis, gingival hyperplasia, gingival hypertrophy: Gingivitis, a common cause of inflammatory gingival enlargement. ... Of all cases of DIGO, about 50% are attributed to phenytoin, 30% to cyclosporins and the remaining 10-20% to calcium channel blockers. history of subdural hematoma icd 10 codeWebMany studies show that phenytoin induces the overexpression of these cytokines but, probably, in our study, the drug does not have the same effect because we used gingival … history of subaru legacyWebGingival hyperplasia is a common side effect of conventional antiseizure medications like phenytoin, but very rare with the newer ones. A 14-year-old boy was started on … history of st vincent de paul charityWebThey should be told that mild gingival hyperplasia (gum swelling) has been reported. Good dental hygiene decreases its incidence and severity. ... phenytoin, carbamazepine, or phenobarbital) than in healthy volunteers. In such patients, the mean area under the felodipine plasma concentration-time curve was also reduced to approximately 6% of ... history of structural analysisWebOct 7, 2024 · Phenytoin-induced gingival overgrowth is a well known and frequently reported gingival lesion, which was first detected in 1939. This case report consists of phenytoin usage, duration and poor ... honda in tyler txWebGingival hyperplasia from phenytoin. Gingival hyperplasia can result in some patients who are taking the anti- seizure medication phenytoin. About 50% of those taking phenytoin will have swelling or overgrowth of their gum tissue. Image Source: SPL / Science Source. Text Source: National Library of Medicine. The Open Dentistry Journal. history of subprime mortgage crisis