Sash1 protein
Webb17 mars 2016 · SAM- and SH3-domain containing 1 (SASH1) is a recently identified tumor suppressor gene that is required in the tumorigenesis of breast and other solid carcinomas. The SASH1 protein contains SH3 and SAM domains, indicating that it may serve an important role in intracellular signal transduction. The purpose of the present study was … Webb12 mars 2024 · As already seen for the first two SLy-family members, the SASH1-protein is able to shuttle between the cytoplasmic and the nuclear cell compartment. Although …
Sash1 protein
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WebbResults: SASH1 was expressed in human vascular cells (HAECs, smooth muscle cells) and in monocytes/macrophages. Its tissue expression was significantly higher in the … Webb8 nov. 2016 · Expression of the SASH1 protein is reduced in a range of human cancers and has been implicated in apoptotic cancer cell death. This study investigated whether …
Webb15 aug. 2003 · SAM and SH3 domain-containing protein 1 Gene names Name Sash1 Organism names Organism Mus musculus (Mouse) Taxonomic identifier 10090 NCBI … Webb10 nov. 2016 · Many proteins have been shown to be cleaved by caspases during apoptosis including the multifunctional protein PARP1 and the human DNA repair nuclease Exo1. 32 The cleavage of SASH1 was shown to ...
Webb25 okt. 2024 · SASH1 is a scaffold protein belonging to the same family as SASH3. Unlike the dimerization seen in SASH3's SAM domain, our SEC-MALS and SE-HPLC showed that SAM1 exists primarily as a less compact ... WebbSASH1 is part of cluster 63 Astrocytes - Nervous system maintenance with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated …
WebbSASH1 gene, which belongs to a member of the SLY family of signal adapter proteins, has been found to suppress the proliferation of tumors. 7 Extensive observations suggested that SASH1 may suppress tumor cell proliferation, migration and invasion in large number of cancer cells. 8–10 In a recent study, authors have demonstrated that autosomal …
WebbImmune cell - SASH1 - The Human Protein Atlas SASH1 IMMUNE CELL CELL LINEAGES Immune cell proteome IMMUNE CELL TYPE EXPRESSION (RNA)i HPA dataseti Lineage … planetary hydraulic motorWebb28 maj 2024 · SASH1 protein expression was almost 2.5-fold higher in astrocytes than in C6 glioma cells. After the astrocytes were treated with SASH1 siRNA for 3 days, the SASH1 mRNA and protein levels... planetary imaging preprocessor downloadWebb15 okt. 2024 · 2.6. HMGB1 siRNA treatment. We investigated the effects of extracellular HMGB1 on SASH1 gene expression by applying 100 ng/mL of HMGB1 recombinant protein (rHMGB1, 1690-HMB, R&D Systems Co.) to the astrocyte cultures for 60 h and subsequently detecting SASH1 expression through qRT-PCR and WB analysis. The … planetary imaging cameras bestWebb26 sep. 2012 · SASH1 antibody was purchased from Bethyl laboratories Inc. (Montgomery, MA, USA) and the primary GAPDH antibody was purchased from Proteintech Group (Chicago, IL, USA). Cell proliferation assay Proliferation assay was carried out to assess cell viability in the A-375 (SASH1), A-375 (EGFP) and A-375 cell lines. planetary imaging cameraWebb15 okt. 2024 · SASH1 is a scaffold protein containing SAM (sterile alpha motif) and SH3 domains [19], [20], [21]. The SAM domain, originally observed in drosophila, can dimerize with other SAM or non-SAM domain containing proteins yielding oligomeric platforms for cell signaling involving translocation from the cytoplasm to the nucleus [20], [21]. planetary hydrogen nova scotiaWebbAll members of the SLy/SASH1-protein family contain a bipartite nuclear localization signal (NLS), a central Src homology 3 (SH3) domain and a sterile α motif (SAM) in their C … planetary imaging preprocessor youtubeWebbChloropyramine-DataSheet-生命科学试剂-MCE.pdf,Hotline: 400-820-3792 Inhibitors • Screening Libraries • Proteins www.MedChemE Chloropyramine Cat. No.: HY-119995 CAS No.: 59-32-5 分⼦式: C₁₆H₂₀ClN₃ 分⼦量: 289.8 作⽤靶点: Apoptosis; Histamine Receptor 作⽤通路: Apoptosis; GPCR/G Protein; Immunology/Inflammation planetary imaging preprocessor下载