Web1 Aug 2024 · Alternative pre-mRNA splicing is a pervasive cellular process that expands the transcriptome relative to the genome through the differential use of exons or portions thereof (Nilsen and Graveley 2010; Blencowe 2024).As such, alternative splicing contributes to proteome complexity among higher eukaryotes and plays an important role in … Web3 Aug 2012 · A 1.2 kb open reading frame of the Pp CHS (Acession No: DQ 275627.2) ... a more flexible and less compact structure which agrees well with the calculated total energy of Cys 170 Arg of −65.03 indicating a decrease of the mutant’s structure stability. On the other hand, for the substituted serine residue, due to the presence of a smaller ...
Alternative splicing and cancer: insights, opportunities, and ...
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